Modeling learning effects in neuropsychological tests

 
   Lead Investigator:    Daniel Gillen
   Institution      :    University of California, Irvine
   E-Mail           :    dgillen@uci.edu
   Proposal ID      :    962



   Proposal Description:
   This project will develop mixed effects models to quantify the trajectory of  patient scores on specific neuropsychological tests repeatedly performed on ADC  patients.  Marginal and individual-level trajectories will be estimated and  stratified by patient diagnosis (Normal, MCI, Dementia).  We hypothesize that  tests within the standard battery will differ with respect to the learning  effect (as defined by positive trajectory over time) among normal subjects,  while MCI and Dementia diagnosed subjects will show consistent declines over  time.